Steroids cause osteoporosis
نویسندگان
چکیده
منابع مشابه
Steroids and osteoporosis: the quest for mechanisms.
Advances made during the last 35 years have improved our understanding of the mechanisms of steroid hormone action on bone and how physiologic, pathologic, or iatrogenic changes in hormone levels can lead to increased fracture risk. Estrogens, androgens, and glucocorticoids alter the cellular composition of bone by regulating the supply and lifespan of osteoclasts and osteoblasts. Additionally,...
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Diabetes and osteoporosis are both frequent disorders. By chance they may thus occur together. However, evidence suggests that osteoporosis defined by bone scans (DXA) occurs more frequent than expected in type 1 diabetes (T1D) and less frequent than expected in T2D (1). The latter may be explained by differences in body size – T2D patients being more obese than the general population and bone ...
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In this article, we review published preclinical and clinical studies that examine the role of female ovarian steroids (estrogen and progesterone) in epilepsy. Its effects on the reproductive and endocrine system are well known but a large and growing body of evidences indicates that the hormones also exert neuroprotective effects on the central nervous system. Estrogen crosses the blood-brain ...
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Male age-related bone loss is caused, at least in part, by hypogonadism that occurs with advancing age. The study of the effects of sex steroids on bone physiology in men has recently highlighted the central role of estrogens on bone pathophysiology. This review focuses on particular aspects of bone physiology and pathophysiology in aging men, noting both the similarities to and the differences...
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BACKGROUND The exact cause of osteoporosis in patients with sickle cell disease (SCD) is not known, and various hypotheses have been put forward. AIM To assess the effect of sex steroids on bone mass in SCD patients. SETTINGS AND DESIGN In King Fahd Hospital of the university, Alkhobar, Saudi Arabia, a cross-sectional study was carried out. MATERIALS AND METHODS All patients known to suff...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2002
ISSN: 0003-4967
DOI: 10.1136/ard.61.1.1-a